SCHEMBL31034828

SCHEMBL31034828

C[n+]1ccc(C#N)cc1.O=[N+]([O-])[O-]

nearest known ligand 0.75

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 3/20 0.75
FBP1 P09467 5/20 0.43
VCAM1 P19320 3/20 0.41
CYP2A6 P11509 2/20 0.39
ALDH1A1 P00352 1/20 0.38
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
TSHR P16473 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5455838 0.87
Hydrochloric Acid SCHEMBL5831783 0.84 HDAC8 (0.95) HDAC8CYP2A6ALDH1A1CA2TSHR
Iodide SCHEMBL23131038 0.84 HDAC8 (0.95) HDAC8CYP2A6ALDH1A1CA2TSHR
Iodide SCHEMBL23131037 0.84 HDAC8 (0.95) HDAC8CYP2A6ALDH1A1CA2TSHR
Iodide SCHEMBL7051892 0.84 HDAC8 (0.95) HDAC8CYP2A6ALDH1A1CA2TSHR
SCHEMBL23131039 0.78 HDAC8 (0.82) HDAC8CYP2A6ALDH1A1CA2TSHR
SCHEMBL5483989 0.77 HDAC8 (0.64) HDAC8CYP2A6ALDH1A1CA1CA2
SCHEMBL5831908 0.73 HDAC8 (0.58) HDAC8CYP2A6ALDH1A1CA1CA2
SCHEMBL6238003 0.71 HDAC8 (0.67) HDAC8CYP2A6ALDH1A1TSHRMAPT
SCHEMBL577736 0.71 HDAC8 (0.67) HDAC8CYP2A6ALDH1A1CA2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4414359-A1 CATALYTIC PROCESS FOR THE PREPARATION OF AMIDES Università di Pisa (IT) 2024-08-14 EP disclosed