Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.95 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CHAT | P28329 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL23131037 | 1.00 | HDAC8 (0.95) | HDAC8CYP2A6ALDH1A1TSHRCHAT | |
| SCHEMBL5455838 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL5831783 | 0.95 | HDAC8 (0.95) | HDAC8CYP2A6ALDH1A1TSHRCA12 | |
| Iodide SCHEMBL23131038 | 0.95 | HDAC8 (0.95) | HDAC8CYP2A6ALDH1A1TSHRCHAT | |
| SCHEMBL23131039 | 0.88 | HDAC8 (0.82) | HDAC8CYP2A6ALDH1A1TSHRCHAT | |
| SCHEMBL31034828 | 0.84 | HDAC8 (0.75) | HDAC8CYP2A6ALDH1A1TSHRCA2 | |
| SCHEMBL6238003 | 0.80 | HDAC8 (0.67) | HDAC8CYP2A6ALDH1A1TSHRCHAT | |
| SCHEMBL577736 | 0.80 | HDAC8 (0.67) | HDAC8CYP2A6ALDH1A1TSHRCA12 | |
| SCHEMBL5483989 | 0.78 | HDAC8 (0.64) | HDAC8CYP2A6ALDH1A1CA12CA2 | |
| SCHEMBL5487286 | 0.75 | HDAC8 (0.60) | HDAC8CYP2A6ALDH1A1TSHRCHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10961224-B2 | Triazinium cation forms and methods of making thereof | LOYOLA UNIVERSITY NEW ORLEANS (US) | 2021-03-30 | — | — | US | claimed |
| WO-2018183749-A1 | TRIAZINIUM CATION FORMS AND METHODS OF MAKING THEREOF | LOYOLA UNIVERSITY NEW ORLEANS (US) | 2018-10-04 | — | — | WO | claimed |
| US-20030034480-A1 | Conversion of non-conducting polymers to conducting polymers | BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS, THE | 2003-02-20 | — | — | US | claimed |
| WO-2001051994-A1 | CONVERSION OF NON-CONDUCTING POLYMERS TO CONDUCTING POLYMERS | THE BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS (US) | 2001-07-19 | — | — | WO | claimed |
| US-4758312-A | Adding colorless electrochemically active compound having positive reduction potential | NALCO CHEMICAL COMPANY (US) | 1988-07-19 | — | — | US | claimed |
| JP-55142050-A | — | — | None | — | — | JP | disclosed |
| EP-4414359-A1 | CATALYTIC PROCESS FOR THE PREPARATION OF AMIDES | Università di Pisa (IT) | 2024-08-14 | — | — | EP | disclosed |
| US-10961224-B2 | Triazinium cation forms and methods of making thereof | LOYOLA UNIVERSITY NEW ORLEANS (US) | 2021-03-30 | — | — | US | disclosed |
| WO-2018183749-A1 | TRIAZINIUM CATION FORMS AND METHODS OF MAKING THEREOF | LOYOLA UNIVERSITY NEW ORLEANS (US) | 2018-10-04 | — | — | WO | disclosed |
| US-20030034480-A1 | Conversion of non-conducting polymers to conducting polymers | BOARD OF GOVERNORS FOR HIGHER EDUCATION, STATE OF RHODE ISLAND AND PROVIDENCE PLANTATIONS, THE | 2003-02-20 | — | — | US | disclosed |
| EP-0174632-B1 | ANTI-MICROBIAL N-(1-(ALKYL OR ARYLMETHYL)-4(1H)-PYRIDINYLIDINE)ALKANAMINES AND ACID ADDITION SALTS THEREOF AND PROCESS FOR PREPARATION, METHODS OF USE AND COMPOSITIONS THEREOF | STERLING DRUG INC. (US) | 1990-02-07 | — | — | EP | disclosed |
| US-4839372-A | ANTIPLAQUE AGENTS | STERLING DRUG INC. (US) | 1989-06-13 | — | — | US | disclosed |
| US-4758312-A | Adding colorless electrochemically active compound having positive reduction potential | NALCO CHEMICAL COMPANY (US) | 1988-07-19 | — | — | US | disclosed |
| EP-0237738-A2 | Method for in situ corrosion detection using electrochemically active compounds | NALCO CHEMICAL COMPANY (US) | 1987-09-23 | — | — | EP | disclosed |
| US-4683035-A | Method for in situ corrosion detection using electrochemically active compounds | NALCO CHEMICAL COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| US-4598082-A | DENTISTRY | STERLING DRUG INC. (US) | 1986-07-01 | — | — | US | disclosed |
| EP-0174632-A1 | Anti-microbial N-(1-(alkyl or arylmethyl)-4(1H)-pyridinylidine)alkanamines and acid addition salts thereof and process for preparation, methods of use and compositions thereof | STERLING DRUG INC. (US) | 1986-03-19 | — | — | EP | disclosed |
| JP-S55142050-A | LACQUER COMPOSITION FOR HIGHLY DIELECTRIC FILM | MATSUSHITA ELECTRIC IND CO LTD | 1980-11-06 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10961224-B2 | Triazinium cation forms and methods of making thereof | MITF, SOD1, TYR | HDAC8 2288/4885CYP2A6 2600/4885ALDH1A1 3460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.