Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23887133 | 0.87 | AKT1 (0.52) | AKT1AKT2AKT3PIK3CAESR1 | |
| SCHEMBL31035117 | 0.83 | AKT1 (0.48) | AKT1AKT2AKT3CDK2PIK3CA | |
| SCHEMBL31035252 | 0.81 | AKT1 (0.51) | AKT1AKT2AKT3CDK2PIK3CA | |
| SCHEMBL31035139 | 0.81 | AKT1 (0.46) | AKT1AKT2AKT3CDK2PIK3CA | |
| SCHEMBL23887233 | 0.77 | PRKDC (0.50) | PIK3CAP2RY12 | |
| SCHEMBL31035280 | 0.75 | NPC1 (0.51) | MAPTTP53TSHRNPC1 | |
| SCHEMBL31035163 | 0.74 | AKT1 (0.47) | AKT1AKT2AKT3PIK3CAP2RY12 | |
| SCHEMBL23887082 | 0.73 | PIK3CA (0.56) | AKT1AKT2AKT3PIK3CA | |
| SCHEMBL23886992 | 0.73 | AKT1 (0.60) | AKT1AKT2AKT3PIK3CA | |
| SCHEMBL31035349 | 0.73 | PIK3CA (0.57) | AKT1AKT2AKT3PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680612-A1 | CHEMICAL COMPOUNDS | AN2 Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192309-A1 | CHEMICAL COMPOUNDS | REACTIVE BIOSCIENCES, INC. (US) | 2024-09-19 | — | — | WO | disclosed |