Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | PRKDC | P78527 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HK1 | P19367 | 1/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31035311 | 0.87 | PRKDC (0.61) | NPC1KMT2ANR2E3PRKDCSMN1; SMN2 | |
| SCHEMBL30081607 | 0.86 | AKT1 (0.46) | NPC1KMT2ANR2E3MAPTPRKDC | |
| SCHEMBL31035236 | 0.84 | PRKDC (0.42) | NPC1KMT2ANR2E3MAPTPRKDC | |
| SCHEMBL31035542 | 0.76 | PIK3CA (0.50) | MAPTPRKDCALPGKDM4EALDH1A1 | |
| SCHEMBL30081540 | 0.75 | KMT2A (0.51) | NPC1KMT2ANR2E3MAPTPRKDC | |
| SCHEMBL31035223 | 0.75 | AKT1 (0.42) | NPC1MAPTTP53TSHR | |
| SCHEMBL31035410 | 0.74 | KDM4E (0.44) | NPC1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL10901602 | 0.72 | ALDH1A1 (0.54) | NPC1KMT2AMAPTPRKDCSMN1; SMN2 | |
| SCHEMBL29253032 | 0.72 | KMT2A (0.43) | NPC1KMT2ANR2E3MAPTPRKDC | |
| SCHEMBL29003817 | 0.72 | NPC1 (0.44) | NPC1KMT2AMAPTPRKDCTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680612-A1 | CHEMICAL COMPOUNDS | AN2 Therapeutics, Inc. (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024192309-A1 | CHEMICAL COMPOUNDS | REACTIVE BIOSCIENCES, INC. (US) | 2024-09-19 | — | — | WO | disclosed |