SCHEMBL31035486

SCHEMBL31035486

Cc1c(N2CCC(C)(C)CC2)oc2c(C(C)Br)cc(C(F)(F)F)cc2c1=O

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 18/20 0.47
AKT1 P31749 1/20 0.47
AKT2 P31751 1/20 0.47
AKT3 Q9Y243 1/20 0.47
IDO1 P14902 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31035230 0.86 AKT1 (0.49) PIK3CAAKT1AKT2AKT3
SCHEMBL23886992 0.86 AKT1 (0.60) PIK3CAAKT1AKT2AKT3
SCHEMBL23895955 0.82 PIK3CA (0.63) PIK3CA
SCHEMBL31035324 0.81 AKT1 (0.52) PIK3CAAKT1AKT2AKT3
SCHEMBL31035332 0.80 AKT1 (0.46) PIK3CAAKT1AKT2AKT3IDO1
SCHEMBL31035349 0.79 PIK3CA (0.57) PIK3CAAKT1AKT2AKT3
SCHEMBL31035326 0.79 PIK3CA (0.59) PIK3CAAKT1AKT2AKT3
SCHEMBL31035343 0.76 PIM1 (0.40) PIK3CAAKT1AKT2AKT3
SCHEMBL31035117 0.75 AKT1 (0.48) PIK3CAAKT1AKT2AKT3
SCHEMBL23895960 0.75 PIK3CA (0.63) PIK3CAAKT1AKT2AKT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680612-A1 CHEMICAL COMPOUNDS AN2 Therapeutics, Inc. (US) 2026-01-21 EP disclosed
WO-2024192309-A1 CHEMICAL COMPOUNDS REACTIVE BIOSCIENCES, INC. (US) 2024-09-19 WO disclosed