Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.33 |
| ▸ | RELA | Q04206 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31035876 | 0.79 | PDE10A (0.39) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL720360 | 0.78 | SMN1; SMN2 (0.50) | USP7SMN1; SMN2NPC1NFKB1RAB9A | |
| SCHEMBL15767035 | 0.76 | GRM5 (0.44) | PARP1SMN1; SMN2MCHR1 | |
| SCHEMBL12777909 | 0.76 | PARP1 (0.38) | PARP1USP7SMN1; SMN2NPC1NFKB1 | |
| SCHEMBL1905278 | 0.75 | KDM4E (0.38) | PARP1USP7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL19497542 | 0.73 | MCHR1 (0.44) | PARP1USP7SMN1; SMN2CA2MCHR1 | |
| SCHEMBL23530832 | 0.72 | NOTUM (0.43) | PARP1USP7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4889270 | 0.72 | PARP1 (0.39) | PARP1USP7SMN1; SMN2NPC1NFKB1 | |
| SCHEMBL25670702 | 0.72 | KDM4E (0.41) | PARP1USP7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28535736 | 0.71 | TLR9 (0.57) | PARP1SMN1; SMN2NPC1NFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118434744-A | Nitrogen-containing macrocyclic compound, and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2024-08-02 | — | — | CN | disclosed |