Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15598268 | 0.98 | HPGD (0.77) | HPGDL3MBTL1LMNATSHRTRPV1 | |
| SCHEMBL27381884 | 0.89 | HPGD (0.83) | HPGDL3MBTL1LMNATSHRTRPV1 | |
| SCHEMBL13287459 | 0.88 | HPGD (0.97) | HPGDL3MBTL1LMNATSHRTRPV1 | |
| SCHEMBL5933901 | 0.88 | HPGD (0.97) | HPGDL3MBTL1LMNATSHRTRPV1 | |
| SCHEMBL15548702 | 0.88 | HDAC3 (0.72) | HPGDL3MBTL1LMNATSHRGAA | |
| SCHEMBL31035861 | 0.87 | TRPV1 (0.73) | HPGDL3MBTL1LMNATSHRTRPV1 | |
| SCHEMBL31036003 | 0.87 | TRPV1 (0.73) | HPGDL3MBTL1LMNATSHRTRPV1 | |
| SCHEMBL31035980 | 0.87 | TRPV1 (0.73) | HPGDL3MBTL1LMNATSHRTRPV1 | |
| SCHEMBL1690856 | 0.87 | HPGD (0.71) | HPGDL3MBTL1ALDH1A1 | |
| SCHEMBL18257127 | 0.86 | L3MBTL1 (0.84) | HPGDL3MBTL1LMNATSHRTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |