Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.50 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339367 | 0.92 | PRKCI (0.55) | PRKCIPIK3CBATAD2CYP2A6CYP3A4 | |
| SCHEMBL13209488 | 0.83 | PRKCI (0.52) | PRKCIPIK3CBCYP2A6CYP3A4TSHR | |
| SCHEMBL17827631 | 0.80 | PRKCI (0.46) | PRKCIPIK3CBCYP2A6CYP3A4TSHR | |
| SCHEMBL29263656 | 0.78 | PRKCI (0.53) | PRKCIPIK3CBCYP2A6HSD11B1PKM | |
| SCHEMBL15899338 | 0.78 | PRKCI (0.58) | PRKCIPIK3CBCYP2A6CYP3A4TSHR | |
| SCHEMBL18683804 | 0.78 | PRKCI (0.60) | PRKCIPIK3CBCYP2A6HSD11B1PKM | |
| SCHEMBL20660663 | 0.77 | ALDH1A1 (0.57) | PRKCIPIK3CBCYP2A6CYP3A4TSHR | |
| SCHEMBL20660849 | 0.77 | ALDH1A1 (0.57) | PRKCIPIK3CBCYP2A6CYP3A4TSHR | |
| SCHEMBL15730252 | 0.76 | PRKCI (0.46) | PRKCIPIK3CBCYP2A6HSD11B1PKM | |
| SCHEMBL18239894 | 0.76 | PRKCI (0.46) | PRKCIPIK3CBCYP2A6HSD11B1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255685-A | Tricyclic compound, pharmaceutical composition and application thereof | 珂阑(上海)医药科技有限公司 | 2024-06-28 | — | — | CN | disclosed |