Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12881233 | 0.91 | SLC6A4 (0.68) | SLC6A4HTR1A | |
| SCHEMBL30468389 | 0.85 | SLC6A4 (0.69) | SLC6A4HTR1A | |
| SCHEMBL30320095 | 0.85 | SLC6A4 (0.69) | SLC6A4HTR1A | |
| SCHEMBL15543730 | 0.85 | SLC6A4 (0.69) | SLC6A4HTR1A | |
| SCHEMBL8255694 | 0.85 | SLC6A4 (0.69) | SLC6A4HTR1A | |
| SCHEMBL5234124 | 0.85 | SLC6A4 (0.69) | SLC6A4HTR1A | |
| SCHEMBL6879916 | 0.85 | SLC6A4 (0.69) | SLC6A4HTR1A | |
| SCHEMBL4351901 | 0.85 | SLC6A4 (0.69) | SLC6A4HTR1A | |
| SCHEMBL5791054 | 0.85 | SLC6A4 (0.69) | SLC6A4HTR1A | |
| SCHEMBL11354043 | 0.85 | SLC6A4 (0.68) | SLC6A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104211668-B | The preparation method of a kind of vilazodone intermediate and intermediate | 上海馨远医药科技有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-104211668-A | Preparation method of vilazodone intermediate and intermediate | SHANGHAI BALMXY PHARMACEUTICAL CO LTD | 2014-12-17 | — | — | CN | disclosed |
| CN-103159718-A | Method for preparing vilazodone hydrochloride midbody | NANJING HUAWE MEDICAL SCIENCE & TECHNOLOGY DEV CO LTD | 2013-06-19 | — | — | CN | disclosed |
| US-7799916-B2 | Process for the preparation of 5-(4-[4-(5-cyano-3-indolyl)butyl]-1-piperazinyl)benzofuran-2-carboxamide | MERCK PATENT GMBH (DE) | 2010-09-21 | — | — | US | disclosed |
| EP-1874762-B1 | METHOD FOR THE PRODUCTION OF 5-(4-[4-(5-CYANO-3-INDOLYL)-BUTYL]-1-PIPERAZINYL)-BENZOFURAN-2-CARBOXAMIDE | MERCK PATENT GMBH (DE) | 2009-01-14 | — | — | EP | disclosed |
| US-20080293943-A1 | Process for the Preparation of 5-(4-[4-(5-Cyano-3-Indolyl)Butyl]-1-Piperazinyl)Benzofuran-2-Carboxamide | MERCK PATENT GMBH (DE) | 2008-11-27 | — | — | US | disclosed |
| EP-1874762-A1 | METHOD FOR THE PRODUCTION OF 5-(4-[4-(5-CYANO-3-INDOLYL)-BUTYL]-1-PIPERAZINYL)-BENZOFURAN-2-CARBOXAMIDE | Merck Patent GmbH (DE) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006114202-A1 | METHOD FOR THE PRODUCTION OF 5-(4-[4-(5-CYANO-3-INDOLYL)-BUTYL]-1-PIPERAZINYL)-BENZOFURAN-2-CARBOXAMIDE | MERCK PATENT GMBH (DE) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293943-A1 | Process for the Preparation of 5-(4-[4-(5-Cyano-3-Indolyl)Butyl]-1-Piperazinyl)Benzofuran-2-Carboxamide | IDO1, BRPF3, BRPF1 | SLC6A4 442/4885HTR1A 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.