Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MDM4 | O15151 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 4/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000539 | 1.00 | KMT2A (0.46) | KMT2AMDM4TP53CASP3EPHX2 | |
| SCHEMBL31000653 | 1.00 | KMT2A (0.46) | KMT2AMDM4TP53CASP3EPHX2 | |
| SCHEMBL31000491 | 0.90 | CASP3 (0.50) | KMT2AMDM4TP53CASP3EPHX2 | |
| SCHEMBL12069026 | 0.90 | CASP3 (0.50) | KMT2AMDM4TP53CASP3EPHX2 | |
| SCHEMBL9995014 | 0.90 | CASP3 (0.50) | KMT2AMDM4TP53CASP3EPHX2 | |
| SCHEMBL17703894 | 0.90 | CASP3 (0.50) | KMT2AMDM4TP53CASP3EPHX2 | |
| SCHEMBL21243785 | 0.90 | CASP3 (0.50) | KMT2AMDM4TP53CASP3EPHX2 | |
| SCHEMBL31000544 | 0.85 | KMT2A (0.46) | KMT2AMDM4TP53CASP3EPHX2 | |
| SCHEMBL31000630 | 0.85 | KMT2A (0.46) | KMT2AMDM4TP53CASP3EPHX2 | |
| SCHEMBL31080829 | 0.85 | MDM4 (0.48) | KMT2AMDM4TP53CASP3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658667-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | Merck Sharp & Dohme LLC (US) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024163691-A1 | CYCLIC PEPTIDES FOR INHIBITING TNF RECEPTOR 1 ACTIVITY | MERCK SHARP & DOHME LLC (US) | 2024-08-08 | — | — | WO | disclosed |