Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842136 | 0.91 | KIF18A (0.66) | KIF18A | |
| SCHEMBL31037916 | 0.86 | KIF18A (0.51) | KIF18A | |
| SCHEMBL31037914 | 0.85 | KIF18A (0.49) | KIF18A | |
| SCHEMBL31037924 | 0.84 | KIF18A (0.39) | KIF18A | |
| SCHEMBL31694763 | 0.84 | KIF18A (0.50) | KIF18A | |
| SCHEMBL31613841 | 0.82 | KIF18A (0.62) | KIF18A | |
| SCHEMBL31694726 | 0.82 | KIF18A (0.58) | KIF18A | |
| SCHEMBL31694778 | 0.81 | KIF18A (0.53) | KIF18A | |
| SCHEMBL31546238 | 0.81 | KIF18A (0.46) | KIF18A | |
| SCHEMBL31037905 | 0.81 | KIF18A (0.49) | KIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118666851-A | Condensed ring KIF18A inhibitor compound, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-09-20 | — | — | CN | disclosed |