Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 9/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22362856 | 1.00 | EED (0.36) | EEDABL1LRRK2HPGDCA2 | |
| SCHEMBL5417502 | 0.87 | EED (0.36) | EEDHPGDALDH1A1L3MBTL1KDM4E | |
| SCHEMBL500770 | 0.85 | EED (0.37) | EEDGNRHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31038078 | 0.84 | EED (0.40) | EEDGNRHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL22363092 | 0.84 | EED (0.40) | EEDGNRHRALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28616526 | 0.84 | EED (0.39) | EEDALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL14738945 | 0.82 | EED (0.35) | EEDGNRHR | |
| SCHEMBL22362980 | 0.81 | ABL1 (0.35) | EEDABL1LRRK2GAA | |
| SCHEMBL22380056 | 0.81 | ACHE (0.38) | EEDABL1LRRK2HPGDCA2 | |
| SCHEMBL28642389 | 0.81 | EED (0.34) | EED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454081-B | Imidazopyridinyl compounds and their use for the treatment of proliferative diseases | 第一生物治疗股份有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-113454082-B | Imidazopyridinyl compounds and their use for the treatment of neurodegenerative diseases | 第一生物治疗股份有限公司 | 2024-07-02 | — | — | CN | disclosed |