Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16298733 | 1.00 | KDM4E (0.53) | KDM4ELMNARXFP1ALDH1A1HPGD | |
| SCHEMBL24388761 | 0.86 | TOP2A (0.48) | KDM4EALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL15426357 | 0.83 | KDM4E (0.60) | KDM4ELMNARXFP1ALDH1A1HPGD | |
| SCHEMBL171055 | 0.82 | TOP2A (0.62) | KDM4EALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL29504749 | 0.82 | TOP2A (0.62) | KDM4EALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL12854009 | 0.80 | TOP2A (0.60) | KDM4EALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL9953869 | 0.79 | AGPAT2 (0.47) | KDM4ELMNARXFP1ALDH1A1HPGD | |
| SCHEMBL30969124 | 0.78 | KLK7 (0.67) | KDM4ERXFP1ALDH1A1HPGDRAB9A | |
| SCHEMBL10563631 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1HPGDRAB9AMAPT | |
| SCHEMBL11644982 | 0.78 | KDM4E (0.62) | KDM4ELMNARXFP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118439997-A | Synthesis method and application of aryl ortho-carbon hydrogen bond functionalization | 云南民族大学 | 2024-08-06 | — | — | CN | disclosed |