Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.67 |
| ▸ | KLK14 | Q9P0G3 | 3/20 | 0.67 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.67 |
| ▸ | CTSG | P08311 | 2/20 | 0.67 |
| ▸ | CTRC | Q99895 | 2/20 | 0.67 |
| ▸ | C1R | P00736 | 7/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | F2 | P00734 | 2/20 | 0.62 |
| ▸ | PLG | P00747 | 1/20 | 0.62 |
| ▸ | KLK1 | P06870 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.62 |
| ▸ | C1S | P09871 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | ELANE | P08246 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KLK3 | P07288 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9475884 | 0.84 | C1R (0.78) | C1RKMT2AF2PLGKLK1 | |
| SCHEMBL29791056 | 0.84 | C1R (0.78) | C1RKMT2AF2PLGKLK1 | |
| SCHEMBL18963257 | 0.82 | C1R (0.76) | C1RKMT2AF2PLGKLK1 | |
| SCHEMBL9475739 | 0.82 | C1R (0.76) | C1RKMT2AF2PLGKLK1 | |
| SCHEMBL2537274 | 0.81 | ELANE (0.73) | C1RKMT2AF2PLGKLK1 | |
| SCHEMBL30914649 | 0.81 | ELANE (0.73) | C1RKMT2AF2PLGKLK1 | |
| SCHEMBL17554106 | 0.81 | ELANE (0.60) | C1RKMT2AF2PLGKLK1 | |
| SCHEMBL18352965 | 0.80 | KLK7 (1.00) | KLK7KLK14KLK5CTSGCTRC | |
| SCHEMBL913682 | 0.80 | C1R (0.68) | C1RKMT2AF2PLGKLK1 | |
| SCHEMBL272287 | 0.79 | ELANE (0.81) | C1RKMT2AF2PLGKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240180915-A1 | OIL-IN-WATER EMULSION OF 6-ETHOXY-7-METHOXY-2-(2-METHYLSULFANYLPHENYL)-3,L-BENZOXAZIN-4-ONE | SIXERA PHARMA AB (SE) | 2024-06-06 | — | — | US | disclosed |