Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31038218 | 0.82 | LRRK2 (0.51) | LRRK2HRH4CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL25199948 | 0.82 | LRRK2 (0.51) | LRRK2HRH4CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL25559023 | 0.80 | LRRK2 (0.45) | LRRK2HRH4CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL31038219 | 0.80 | KDM4E (0.50) | LRRK2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL25188588 | 0.80 | KDM4E (0.50) | LRRK2KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL25560002 | 0.74 | SMO (0.37) | MAPTSMN1; SMN2 | |
| SCHEMBL21452764 | 0.71 | RPS6KB1 (0.45) | HRH4CYP1A2ALDH1A1HSD17B10KDM4E | |
| SCHEMBL31614476 | 0.71 | OGA (0.38) | HRH4CYP1A2ALOX15TSHRCYP2C19 | |
| SCHEMBL31205731 | 0.71 | RIPK1 (0.48) | LRRK2KDM4E | |
| SCHEMBL31383394 | 0.70 | CYP2C19 (0.58) | HRH4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118510775-A | Isoxazolidines as RIPK1 inhibitors and their use | 建新公司 | 2024-08-16 | — | — | CN | claimed |
| CN-118510775-A | Isoxazolidines as RIPK1 inhibitors and their use | 建新公司 | 2024-08-16 | — | — | CN | disclosed |