Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | PRKCB | P05771 | 2/20 | 0.49 |
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | PRKCH | P24723 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MERTK | Q12866 | 7/20 | 0.47 |
| ▸ | AXL | P30530 | 5/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13156495 | 1.00 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2TAAR1PRKCB | |
| SCHEMBL13156526 | 0.90 | MERTK (0.51) | PRKCBPRKCAPRKCEPRKCGPRKCH | |
| SCHEMBL3096606 | 0.90 | MERTK (0.51) | PRKCBPRKCAPRKCEPRKCGPRKCH | |
| SCHEMBL13181608 | 0.80 | HDAC3 (0.48) | NPC1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL13156519 | 0.80 | NPC1 (0.52) | NPC1RAB9AGAAMAPTMEN1 | |
| SCHEMBL3089032 | 0.80 | NPC1 (0.52) | NPC1RAB9AGAAMAPTMEN1 | |
| SCHEMBL30583807 | 0.79 | NPC1 (0.62) | NPC1RAB9AGAAMAPTMEN1 | |
| SCHEMBL7864067 | 0.79 | CXCR1 (0.52) | GAAMAPTMEN1KMT2A | |
| SCHEMBL7864070 | 0.79 | CXCR1 (0.52) | GAAMAPTMEN1KMT2A | |
| SCHEMBL27701237 | 0.78 | KCNA5 (0.53) | MAPTMEN1KMT2AMERTKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799934-B2 | Intermediates (synthons) in the synthesis of pharmaceuticals such as oseltamivir and other products; treating the arizidine with the nucleophile in the presence of a biaryl phosphoric acid catalyst | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-09-21 | — | — | US | disclosed |
| US-20090030212-A1 | Enantioselective ring-opening of aziridines | UNIVERSITY OF SOUTH FLORIDA OF TAMPA | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030212-A1 | Enantioselective ring-opening of aziridines | AZI2, ITPA, ADORA2A | NPC1 3406/4885RAB9A 557/4885SMN1; SMN2 3472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.