Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MERTK | Q12866 | 9/20 | 0.49 |
| ▸ | AXL | P30530 | 6/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064031 | 0.89 | KCNA5 (0.51) | KCNA5P2RX7ALDH1A1KDM4EMAPT | |
| SCHEMBL12629181 | 0.86 | P2RX7 (0.52) | KCNA5P2RX7ALDH1A1KDM4EMAPT | |
| SCHEMBL14534809 | 0.86 | MERTK (0.53) | KCNA5P2RX7MERTKAXLMET | |
| SCHEMBL13324324 | 0.86 | P2RX7 (0.52) | KCNA5P2RX7ALDH1A1KDM4EMAPT | |
| SCHEMBL25250950 | 0.84 | BCHE (0.46) | ALDH1A1MAPTMEN1KMT2ASGMS2 | |
| SCHEMBL4075331 | 0.83 | P2RX7 (0.50) | KCNA5P2RX7MERTKAXLMET | |
| SCHEMBL4380010 | 0.83 | KMT2A (0.51) | KCNA5P2RX7ALDH1A1KDM4EMAPT | |
| SCHEMBL14583914 | 0.83 | KMT2A (0.51) | KCNA5P2RX7ALDH1A1KDM4EMAPT | |
| SCHEMBL1928743 | 0.83 | KMT2A (0.51) | KCNA5P2RX7ALDH1A1KDM4EMAPT | |
| SCHEMBL8280167 | 0.83 | KMT2A (0.51) | KCNA5P2RX7ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087764-A | Substituted 5-oxo pyrazoles and [1,2,4]triazoles as antiviral agents | SCHERING CORP (US) | 2007-12-12 | — | — | CN | disclosed |