Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.60 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.54 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20456897 | 1.00 | KDM4E (0.63) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17184425 | 0.89 | KDM4E (0.63) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17184390 | 0.88 | NR4A2 (0.70) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1458088 | 0.85 | KDM4E (0.56) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10210427 | 0.82 | RAB9A (0.55) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2630604 | 0.81 | RAB9A (0.74) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL3178116 | 0.81 | CHEK2 (0.78) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29101816 | 0.79 | KDM4E (0.67) | KDM4ENPC1RAB9AALDH1A1MAPK9 | |
| SCHEMBL29101814 | 0.79 | KDM4E (0.68) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL30637068 | 0.79 | KDM4E (0.68) | KDM4ENPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480009-A | Compositions and methods for modulating short-chain dehydrogenase activity | 卡斯西部储备大学 | 2024-08-13 | — | — | CN | disclosed |