Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25296668 | 1.00 | HSD17B10 (0.36) | HSD17B10PLAUNMT1PPARAHCRTR1 | |
| SCHEMBL29818560 | 0.76 | BDKRB1 (0.35) | HSD17B10PLAUNMT1 | |
| SCHEMBL25212088 | 0.76 | BDKRB1 (0.35) | HSD17B10PLAUNMT1 | |
| SCHEMBL27042006 | 0.72 | PLAU (0.41) | HSD17B10PLAUNMT1MEN1KMT2A | |
| SCHEMBL31501759 | 0.72 | PLAU (0.41) | HSD17B10PLAUNMT1MEN1KMT2A | |
| SCHEMBL31348097 | 0.70 | PPARA (0.40) | PPARAHCRTR1HCRTR2MEN1KMT2A | |
| SCHEMBL14246319 | 0.68 | PPARA (0.38) | PLAUPPARARXFP1 | |
| SCHEMBL20969942 | 0.67 | PPARA (0.40) | PPARA | |
| SCHEMBL31038454 | 0.67 | DYRK1A (0.37) | PLAU | |
| SCHEMBL25256052 | 0.67 | DYRK1A (0.37) | PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118451068-A | Tri-fused ring derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-08-06 | — | — | CN | disclosed |