Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27042006 | 1.00 | PLAU (0.41) | PLAUNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL27070674 | 0.80 | KMT2A (0.41) | NPC1RAB9ASMN1; SMN2MAPK1KMT2A | |
| SCHEMBL17729276 | 0.76 | ALDH1A1 (0.34) | NPC1RAB9ASMN1; SMN2MAPK1KMT2A | |
| SCHEMBL25256052 | 0.74 | DYRK1A (0.37) | PLAUSMN1; SMN2DYRK1AKDM4EALDH1A1 | |
| SCHEMBL31038454 | 0.74 | DYRK1A (0.37) | PLAUSMN1; SMN2DYRK1AKDM4EALDH1A1 | |
| SCHEMBL29818393 | 0.73 | PTK2 (0.50) | DYRK1APTK2 | |
| SCHEMBL25194689 | 0.73 | PTK2 (0.50) | DYRK1APTK2 | |
| SCHEMBL25296668 | 0.72 | HSD17B10 (0.36) | PLAUKMT2AMEN1NMT1RXFP1 | |
| SCHEMBL31038476 | 0.72 | HSD17B10 (0.36) | PLAUKMT2AMEN1NMT1RXFP1 | |
| SCHEMBL31501728 | 0.72 | TRPV1 (0.39) | NPC1RAB9ASMN1; SMN2MAPK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119923398-A | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2025-05-02 | — | — | CN | disclosed |