Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 6/20 | 0.38 |
| ▸ | AKT1 | P31749 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 2/20 | 0.35 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.35 |
| ▸ | LATS1 | O95835 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1365945 | 0.82 | AKT1 (0.48) | NPBWR1AKT2AKT1PRKACAAKT3 | |
| SCHEMBL30060444 | 0.74 | KDM4E (0.41) | NPBWR1AKT2AKT1HSD17B10KDM4E | |
| SCHEMBL3560817 | 0.73 | KDM4E (0.54) | ADORA2AADORA1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL17675343 | 0.72 | IDO1 (0.60) | NPBWR1AKT2AKT1IDO1AURKA | |
| SCHEMBL3561230 | 0.71 | ADORA2A (0.49) | ADORA2AADORA1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL29533228 | 0.70 | AKT2 (0.61) | AKT2AKT1ROCK2RPS6KA3ABL1 | |
| SCHEMBL15849790 | 0.70 | AKT2 (0.61) | AKT2AKT1ROCK2RPS6KA3ABL1 | |
| SCHEMBL16700734 | 0.69 | AKT1 (0.47) | NPBWR1AKT2AKT1 | |
| SCHEMBL25798414 | 0.69 | NPBWR1 (0.44) | NPBWR1AKT2AKT1FDPSEPHB4 | |
| SCHEMBL7262587 | 0.68 | NPBWR1 (0.40) | NPBWR1ADORA2AADORA1AKT2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655296-A1 | CBL-B INHIBITORS | Aurigene Oncology Limited (IN) | 2025-12-03 | — | — | EP | disclosed |
| WO-2024156938-A1 | CBL-B INHIBITORS | ORION CORPORATION (FI) | 2024-08-02 | — | — | WO | disclosed |