Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 18/20 | 0.51 |
| ▸ | JAK3 | P52333 | 18/20 | 0.51 |
| ▸ | EGFR | P00533 | 10/20 | 0.51 |
| ▸ | BTK | Q06187 | 8/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31039885 | 0.95 | BTK (0.52) | LCKJAK3EGFRBTK | |
| SCHEMBL21855223 | 0.88 | JAK3 (0.68) | LCKJAK3EGFRBTK | |
| SCHEMBL31039887 | 0.85 | JAK3 (0.56) | LCKJAK3EGFRBTK | |
| SCHEMBL21855407 | 0.83 | JAK3 (0.67) | LCKJAK3EGFRBTK | |
| SCHEMBL21946730 | 0.82 | JAK3 (0.67) | LCKJAK3EGFRBTK | |
| SCHEMBL29264612 | 0.82 | JAK3 (0.56) | LCKJAK3EGFRBTK | |
| SCHEMBL21946803 | 0.81 | BTK (0.64) | LCKJAK3EGFRBTK | |
| SCHEMBL30011960 | 0.81 | BTK (0.64) | LCKJAK3EGFRBTK | |
| SCHEMBL21946276 | 0.80 | JAK3 (0.71) | LCKJAK3EGFRBTK | |
| SCHEMBL31039874 | 0.80 | JAK3 (0.46) | LCKJAK3EGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118955473-A | Difunctional compounds for degrading BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-113412259-B | Difunctional compounds for degrading BTK via the ubiquitin proteasome pathway | 紐力克斯治疗公司 | 2024-07-16 | — | — | CN | disclosed |