Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | F12 | P00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17299585 | 0.86 | IDO1 (0.54) | HTR1AHTR2AHTR7HTR6IDO1 | |
| SCHEMBL18317374 | 0.86 | KDM4E (0.58) | HTR1AHTR2AHTR7HTR6TDO2 | |
| SCHEMBL18015590 | 0.80 | NPC1 (0.48) | HTR1AHTR2AHTR7HTR6NPC1 | |
| SCHEMBL28252191 | 0.80 | HTR1A (0.51) | HTR1AHTR2AHTR7HTR6NPC1 | |
| SCHEMBL28414868 | 0.77 | IDO1 (0.46) | HTR1AHTR2AHTR7HTR6IDO1 | |
| SCHEMBL29986041 | 0.77 | BCHE (0.58) | HTR1AHTR2AHTR7HTR6NPC1 | |
| SCHEMBL158912 | 0.77 | BCHE (0.58) | HTR1AHTR2AHTR7HTR6NPC1 | |
| SCHEMBL12112873 | 0.77 | MAPT (0.58) | TDO2NPC1RAB9AMAPTKDM4E | |
| SCHEMBL4738173 | 0.76 | HTR1A (0.49) | HTR1AHTR2AHTR7HTR6NPC1 | |
| SCHEMBL31011155 | 0.75 | BCHE (0.57) | HTR1AHTR2AHTR7HTR6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515608-A | Synthesis method of palladium-catalyzed aza-ortho-terphenyl hydrocarbon | 新疆大学 | 2024-08-20 | — | — | CN | disclosed |