Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.30 |
| ▸ | HTR1A known ✓ | P08908 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL31016466 | 0.98 | CYP3A4 (0.39) | CYP3A4TDP1DRD1ESR1ESR2 | |
| SCHEMBL30958560 | 0.98 | CYP3A4 (0.42) | CYP3A4TDP1DRD1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL31606750 | 0.96 | CYP3A4 (0.41) | CYP3A4TDP1DRD1ESR1ESR2 | |
| SCHEMBL15655984 | 0.94 | CYP3A4 (0.42) | CYP3A4TDP1DRD1ESR1ESR2 | |
| Bromide SCHEMBL2452737 | 0.89 | LIPG (0.40) | CYP3A4TDP1DRD1LIPGPPARG | |
| Bromide SCHEMBL30959785 | 0.89 | LIPG (0.40) | CYP3A4TDP1DRD1LIPGPPARG | |
| Bromide SCHEMBL2443467 | 0.87 | LIPG (0.46) | LIPGPPARGPPARA | |
| SCHEMBL15659099 | 0.87 | CYP3A4 (0.37) | CYP3A4TDP1DRD1ESR1ESR2 | |
| Bromide SCHEMBL31201100 | 0.87 | LIPG (0.46) | LIPGPPARGPPARA | |
| SCHEMBL6578136 | 0.87 | LIPG (0.41) | CYP3A4TDP1DRD1LIPGPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118178670-A | Preparation method of novel targeted mitochondrial antioxidant and application of novel targeted mitochondrial antioxidant in resisting autoimmune hepatitis | 华中科技大学 | 2024-06-14 | — | — | CN | claimed |
| CN-119954713-A | Double-component luminous glass and preparation method and application thereof | 中山大学 | 2025-05-09 | — | — | CN | disclosed |
| CN-119241067-A | Preparation method of reconfigurable glass scintillation screen and application of reconfigurable glass scintillation screen in X-ray conformal imaging | 山东大学 | 2025-01-03 | — | — | CN | disclosed |
| CN-118963022-A | Light conversion diffusion plate, preparation method thereof and display device comprising light conversion diffusion plate | 复旦大学义乌研究院 | 2024-11-15 | — | — | CN | disclosed |
| CN-118178670-A | Preparation method of novel targeted mitochondrial antioxidant and application of novel targeted mitochondrial antioxidant in resisting autoimmune hepatitis | 华中科技大学 | 2024-06-14 | — | — | CN | disclosed |
| CN-118178670-A | Preparation method of novel targeted mitochondrial antioxidant and application of novel targeted mitochondrial antioxidant in resisting autoimmune hepatitis | 华中科技大学 | 2024-06-14 | — | — | CN | disclosed |