Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 2/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.48 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31042922 | 0.92 | TRPC5 (0.56) | BRAFPIK3CGRAB9ATRPC4TRPC5 | |
| SCHEMBL31042863 | 0.92 | PCSK9 (0.49) | BRAFPIK3CGTRPC4TRPC5KCNH2 | |
| SCHEMBL31042897 | 0.89 | TRPC5 (0.47) | BRAFPIK3CGRAB9ATRPC4TRPC5 | |
| SCHEMBL31042906 | 0.89 | TRPC5 (0.46) | BRAFPIK3CGRAB9ATRPC4TRPC5 | |
| SCHEMBL31042903 | 0.88 | TRPC4 (0.43) | BRAFPIK3CGRAB9ATRPC4TRPC5 | |
| SCHEMBL31042914 | 0.88 | BRAF (0.49) | BRAFPIK3CGRAB9ATRPC4TRPC5 | |
| SCHEMBL31042873 | 0.87 | TRPC5 (0.47) | BRAFPIK3CGTRPC4TRPC5KCNH2 | |
| SCHEMBL31042882 | 0.87 | TRPC5 (0.49) | BRAFPIK3CGTRPC4TRPC5KCNH2 | |
| SCHEMBL31042908 | 0.85 | TRPC5 (0.55) | BRAFPIK3CGRAB9ATRPC4TRPC5 | |
| SCHEMBL31042918 | 0.83 | MAPK1 (0.51) | TRPC4TRPC5KCNH2KMT2APCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4663640-A1 | XANTHINE COMPOUND AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024164818-A1 | XANTHINE COMPOUND AND USE THEREOF | 中国科学院上海药物研究所 | 2024-08-15 | — | — | WO | disclosed |