Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3333248 | 0.83 | ACACB (0.48) | ACACB | |
| SCHEMBL2120938 | 0.83 | GPR119 (0.64) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL30947672 | 0.83 | GPR119 (0.64) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL3098995 | 0.82 | GPR119 (0.63) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL6356496 | 0.82 | GPR119 (0.59) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL3104760 | 0.81 | GPR119 (0.60) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL25187518 | 0.80 | GPR119 (0.59) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL30893585 | 0.80 | GPR119 (0.59) | GPR119MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL13993542 | 0.79 | GPR119 (0.67) | GPR119KMT2A | |
| SCHEMBL31748202 | 0.79 | GPR119 (0.67) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167490-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008153325-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-12-18 | — | — | WO | disclosed |