Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 4/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470714 | 0.90 | CYP17A1 (0.45) | CYP17A1TOP2ATOP2BSREBF2MAPKAPK2 | |
| SCHEMBL30955400 | 0.84 | RXFP1 (0.40) | CYP17A1TOP2ATOP2BSYKSREBF2 | |
| SCHEMBL28151268 | 0.82 | TOP2A (0.40) | CYP17A1TOP2ATOP2BSREBF2MAPKAPK2 | |
| SCHEMBL17512692 | 0.81 | ATR (0.41) | CYP17A1TOP2ATOP2BSREBF2MAPKAPK2 | |
| SCHEMBL23608484 | 0.79 | SYK (0.39) | CYP17A1TOP2ATOP2BSYKMAPK14 | |
| SCHEMBL29883076 | 0.79 | SYK (0.39) | CYP17A1TOP2ATOP2BSYKMAPK14 | |
| SCHEMBL29703935 | 0.78 | SCN9A (0.40) | CYP17A1SYKSREBF2CA1LCK | |
| SCHEMBL23608697 | 0.78 | SYK (0.39) | CYP17A1TOP2ATOP2BSYKEGLN2 | |
| SCHEMBL23168284 | 0.76 | SREBF2 (0.47) | CYP17A1SREBF2MAPKAPK2MAPK14CA12 | |
| SCHEMBL25751479 | 0.74 | CYP4F2 (0.44) | CYP17A1TOP2ATOP2BSYKMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658647-A1 | TRICYCLIC AZEPINONE DERIVATIVES AS SYSTEM XC INHIBITORS | UCB Biopharma SRL (BE) | 2025-12-10 | — | — | EP | disclosed |
| WO-2024160722-A1 | TRICYCLIC AZEPINONE DERIVATIVES AS SYSTEM XC INHIBITORS | UCB Biopharma SRL (BE) | 2024-08-08 | — | — | WO | disclosed |