Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 7/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 6/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | LATS1 | O95835 | 3/20 | 0.46 |
| ▸ | LATS2 | Q9NRM7 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | TACR2 | P21452 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | KMT5B | Q4FZB7 | 1/20 | 0.43 |
| ▸ | KMT5C | Q86Y97 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30994540 | 0.99 | IL1B (0.55) | IL1BNLRP3KCNH2LATS1LATS2 | |
| SCHEMBL30994534 | 0.92 | IL1B (0.50) | IL1BNLRP3KCNH2LATS1LATS2 | |
| SCHEMBL30213864 | 0.91 | IL1B (0.49) | IL1BNLRP3KCNH2LATS1LATS2 | |
| SCHEMBL29275723 | 0.91 | IL1B (0.49) | IL1BNLRP3KCNH2LATS1LATS2 | |
| SCHEMBL24855364 | 0.90 | IL1B (0.51) | IL1BNLRP3KCNH2LATS1LATS2 | |
| SCHEMBL29180720 | 0.90 | IL1B (0.51) | IL1BNLRP3KCNH2LATS1LATS2 | |
| SCHEMBL30771847 | 0.90 | IL1B (0.51) | IL1BNLRP3KCNH2LATS1LATS2 | |
| SCHEMBL30771829 | 0.90 | IL1B (0.51) | IL1BNLRP3KCNH2LATS1LATS2 | |
| SCHEMBL24855769 | 0.90 | IL1B (0.51) | IL1BNLRP3KCNH2LATS1LATS2 | |
| SCHEMBL30214908 | 0.90 | IL1B (0.51) | IL1BNLRP3KCNH2LATS1LATS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4642772-A1 | NLRP3 INFLAMMASOME INHIBITORS | Astrazeneca AB (SE) | 2025-11-05 | — | — | EP | claimed |
| WO-2024141535-A1 | NLRP3 INFLAMMASOME INHIBITORS | ASTRAZENECA AB (SE) | 2024-07-04 | — | — | WO | claimed |
| EP-4642772-A1 | NLRP3 INFLAMMASOME INHIBITORS | Astrazeneca AB (SE) | 2025-11-05 | — | — | EP | disclosed |
| WO-2024141535-A1 | NLRP3 INFLAMMASOME INHIBITORS | ASTRAZENECA AB (SE) | 2024-07-04 | — | — | WO | disclosed |