SCHEMBL3104372

SCHEMBL3104372

Nc1cc(N)cc(C(=O)N2CCN(C(=O)c3cc(N)cc(N)c3)CC2)c1

nearest known ligand 0.77

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.77
SERPINE1 P05121 1/20 0.57
HPGD P15428 2/20 0.52
HSD11B1 P28845 1/20 0.52
CA12 O43570 2/20 0.49
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA7 P43166 2/20 0.49
CA9 Q16790 2/20 0.49
CA14 Q9ULX7 2/20 0.49
ALDH1A1 P00352 4/20 0.47
TP53 P04637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
GAA P10253 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2014694 0.87 KDM4E (1.00) KDM4ESERPINE1HPGDHSD11B1CA12
SCHEMBL8358325 0.86 KDM4E (0.65) KDM4ESERPINE1HPGDHSD11B1
SCHEMBL15695610 0.86 KDM4E (0.65) KDM4EHPGDL3MBTL1SMN1; SMN2POLB
SCHEMBL27861118 0.86 KDM4E (0.59) KDM4ESERPINE1HPGDHSD11B1ALDH1A1
SCHEMBL14733308 0.85 KDM4E (0.62) KDM4EHPGDL3MBTL1SMN1; SMN2POLB
SCHEMBL27861127 0.83 TSHR (0.69) KDM4ECA12CA1CA2CA7
SCHEMBL13100495 0.82 KDM4E (0.59) KDM4ESERPINE1HPGDHSD11B1CA12
SCHEMBL9999686 0.82 KDM4E (0.68) KDM4EHPGDALDH1A1L3MBTL1SMN1; SMN2
SCHEMBL31350909 0.79 MAOB (0.73) KDM4EHPGDCA12CA1CA2
SCHEMBL21930867 0.79 KDM4E (0.71) KDM4EHPGDHSD11B1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8349971-B2 6,6-polyimide copolymers and processes for preparing them SOLPIT INDUSTRIES, LTD. (JP) 2013-01-08 US claimed
US-20100273955-A1 6,6-Polyimide Copolymers and Processes for Preparing Them SOLPIT INDUSTRIES, LTD. (JP) 2010-10-28 US claimed
US-20130224653-A1 CROSSLINKED POLYIMIDE, COMPOSITION COMPRISING THE SAME AND METHOD FOR PRODUCING THE SAME PI R&D CO., LTD (JP) 2013-08-29 US disclosed
US-20130224653-A1 CROSSLINKED POLYIMIDE, COMPOSITION COMPRISING THE SAME AND METHOD FOR PRODUCING THE SAME PI R&D CO., LTD (JP) 2013-08-29 US disclosed
US-8349971-B2 6,6-polyimide copolymers and processes for preparing them SOLPIT INDUSTRIES, LTD. (JP) 2013-01-08 US disclosed
US-20110136061-A1 CROSSLINKED POLYIMIDE, COMPOSITION COMPRISING THE SAME AND PROCESS FOR PRODUCING THE SAME ITATANI HIROSHI 2011-06-09 US disclosed
US-20110136061-A1 CROSSLINKED POLYIMIDE, COMPOSITION COMPRISING THE SAME AND PROCESS FOR PRODUCING THE SAME ITATANI HIROSHI 2011-06-09 US disclosed
US-20100273955-A1 6,6-Polyimide Copolymers and Processes for Preparing Them SOLPIT INDUSTRIES, LTD. (JP) 2010-10-28 US disclosed
US-20070106056-A1 Crosslinked polyimide, composition comprising the same and method for producing the same PI R&D CO., LTD. (JP) 2007-05-10 US disclosed
US-20070106056-A1 Crosslinked polyimide, composition comprising the same and method for producing the same PI R&D CO., LTD. (JP) 2007-05-10 US disclosed