SCHEMBL14733308

SCHEMBL14733308

Nc1cc(N)cc(C(=O)N2CCOCCOCCOCCOCC2)c1

nearest known ligand 0.62

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.62
PHGDH O43175 1/20 0.53
PKM P14618 1/20 0.53
HPGD P15428 6/20 0.50
TSHR P16473 2/20 0.50
L3MBTL1 Q9Y468 3/20 0.49
POLB P06746 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
NSD2 O96028 1/20 0.49
NR4A1 P22736 1/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
DNMT1 P26358 1/20 0.49
PTPN7 P35236 1/20 0.49
KMT2A Q03164 1/20 0.49
MAPT P10636 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.47
AKR1C3 P42330 1/20 0.47
HSP90AA1 P07900 1/20 0.47
HSP90AB1 P08238 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15695610 0.98 KDM4E (0.65) KDM4EPHGDHPKMHPGDTSHR
SCHEMBL23113264 0.87 HPGD (0.58) KDM4EPHGDHPKMHPGDL3MBTL1
SCHEMBL23113441 0.87 PHGDH (0.59) KDM4EPHGDHPKMHPGDTSHR
SCHEMBL3104372 0.85 KDM4E (0.77) KDM4EHPGDL3MBTL1POLBSMN1; SMN2
SCHEMBL31703347 0.83 KDM4E (0.51) KDM4EPHGDHPKMHPGDTSHR
SCHEMBL30584223 0.83 EPHX2 (0.52) KDM4EHPGDTSHRPOLBSMN1; SMN2
SCHEMBL1013250 0.83 EPHX2 (0.52) KDM4EHPGDTSHRPOLBSMN1; SMN2
SCHEMBL3576242 0.83 L3MBTL1 (0.64) KDM4EHPGDTSHRL3MBTL1POLB
SCHEMBL15570388 0.82 HPGD (0.58) KDM4EHPGDTSHRKMT2ASMN1; SMN2
SCHEMBL30568869 0.81 L3MBTL1 (0.62) KDM4EPKMHPGDTSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130053513-A1 LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT FORMED FROM THE LIQUID CRYSTAL ALIGNMENT AGENT CHI MEI CORPORATION (TW) 2013-02-28 US disclosed
US-20130053513-A1 LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT FORMED FROM THE LIQUID CRYSTAL ALIGNMENT AGENT CHI MEI CORPORATION (TW) 2013-02-28 US disclosed