Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31029093 | 1.00 | S1PR3 (0.48) | S1PR3MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL31029205 | 0.93 | S1PR3 (0.46) | S1PR3MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL31043954 | 0.93 | S1PR3 (0.46) | S1PR3MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL31043854 | 0.90 | MAPT (0.45) | S1PR3MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL31029171 | 0.90 | MAPT (0.45) | S1PR3MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL31043772 | 0.88 | MEN1 (0.48) | S1PR3MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL31043929 | 0.88 | MEN1 (0.43) | S1PR3MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL31029168 | 0.88 | MEN1 (0.48) | S1PR3MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL31029090 | 0.88 | MEN1 (0.43) | S1PR3MEN1KMT2AMAPTNPSR1 | |
| SCHEMBL31043744 | 0.87 | MEN1 (0.51) | MEN1KMT2AMAPTNPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240279215-A1 | NAMPT MODULATORS | CYTOKINETICS, INCORPORATED | 2024-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240279215-A1 | NAMPT MODULATORS | NAMPT, SIRT1, NNT | S1PR3 757/4885MEN1 780/4885KMT2A 1305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.