Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 4/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31044631 | 0.84 | EGLN1 (0.48) | EGLN1FFAR1TBK1CHRNB2CHRNA2 | |
| SCHEMBL28420321 | 0.83 | EGLN1 (0.46) | EGLN1CHRNB2CHRNA2CHRNB4CHRNA3 | |
| SCHEMBL18335098 | 0.78 | EGLN1 (0.44) | EGLN1CHRNB2CHRNA2CHRNB4CHRNA3 | |
| SCHEMBL15808907 | 0.76 | ALDH1A1 (0.47) | FFAR1TBK1HAO1LMNASMN1; SMN2 | |
| SCHEMBL15900548 | 0.73 | EGLN1 (0.53) | EGLN1FFAR1CHRNB2CHRNA2CHRNB4 | |
| SCHEMBL3581884 | 0.73 | TSHR (0.47) | EGLN1FFAR1TBK1HAO1SMN1; SMN2 | |
| SCHEMBL19063445 | 0.72 | EGLN1 (0.49) | EGLN1FFAR1CHRNB2CHRNA2CHRNB4 | |
| SCHEMBL1975968 | 0.71 | FFAR1 (0.48) | EGLN1FFAR1HAO1SMN1; SMN2FFAR4 | |
| SCHEMBL31044554 | 0.70 | EGLN1 (0.44) | EGLN1FFAR1CHRNB2CHRNA2CHRNB4 | |
| SCHEMBL3727102 | 0.70 | DHODH (0.46) | LMNASMN1; SMN2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111285874-B | RET inhibitor, pharmaceutical composition thereof and application thereof | 广东东阳光药业股份有限公司 | 2024-08-09 | — | — | CN | disclosed |