SCHEMBL31046899

SCHEMBL31046899

N#Cc1ccc(S(=O)(=O)Nc2cc(C(F)(F)F)ccc2C(=O)NC23CC(c4ccccc4)(C2)C3)cc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ USP2 O75604 5/20 0.47
▸ USP8 P40818 5/20 0.47
▸ ACLY P53396 3/20 0.46
▸ KDM1A O60341 2/20 0.46
▸ USP36 Q9P275 1/20 0.44
▸ CCR1 P32246 1/20 0.43
▸ CCR2 P41597 1/20 0.43
▸ GPR27 Q9NS67 6/20 0.42
▸ AVPR2 P30518 4/20 0.42
▸ RXFP1 Q9HBX9 1/20 0.41
▸ KCNA5 P22460 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23877475 1.00 USP2 (0.47) USP2USP8ACLYKDM1AUSP36
SCHEMBL23877572 0.88 USP2 (0.49) USP2USP8ACLYKDM1AUSP36
SCHEMBL23877586 0.88 KDM1A (0.47) USP2USP8ACLYKDM1AUSP36
SCHEMBL30547625 0.88 KDM1A (0.47) USP2USP8ACLYKDM1AUSP36
SCHEMBL23877465 0.87 USP2 (0.47) USP2USP8ACLYKDM1AUSP36
SCHEMBL23877568 0.87 USP2 (0.47) USP2USP8ACLYKDM1AUSP36
SCHEMBL29460194 0.87 USP2 (0.47) USP2USP8ACLYKDM1AUSP36
SCHEMBL23141388 0.86 USP2 (0.47) USP2USP8ACLYKDM1AUSP36
SCHEMBL31046888 0.86 USP2 (0.47) USP2USP8ACLYKDM1AUSP36
SCHEMBL23877582 0.86 USP2 (0.47) USP2USP8ACLYKDM1AUSP36

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118791407-A Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives 奥索生物公司 2024-10-18 — — CN disclosed
CN-118638096-A Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives 奥索生物公司 2024-09-13 — — CN disclosed
CN-112204008-B Sulfonylaminobenzamides and sulfonylaminobenzamide derivatives 奥索生物公司 2024-07-05 — — CN disclosed
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