SCHEMBL23877586

SCHEMBL23877586

N#Cc1ccc(S(=O)(=O)Nc2cc(C(F)(F)F)ccc2C(=O)NC23CC(C(F)(F)F)(C2)C3)cc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 4/20 0.47
▸ ACLY P53396 2/20 0.44
▸ USP2 O75604 4/20 0.44
▸ USP8 P40818 4/20 0.44
▸ USP36 Q9P275 1/20 0.42
▸ CCR1 P32246 1/20 0.40
▸ CCR2 P41597 1/20 0.40
▸ RXFP1 Q9HBX9 1/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ GPR27 Q9NS67 5/20 0.39
▸ AVPR2 P30518 3/20 0.39
▸ HTR6 P50406 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30547625 1.00 KDM1A (0.47) KDM1AACLYUSP2USP8USP36
SCHEMBL23877475 0.88 USP2 (0.47) KDM1AACLYUSP2USP8USP36
SCHEMBL31046899 0.88 USP2 (0.47) KDM1AACLYUSP2USP8USP36
SCHEMBL23879636 0.88 KDM1A (0.50) KDM1AACLYUSP2USP8USP36
SCHEMBL23877472 0.88 KDM1A (0.50) KDM1AACLYUSP2USP8USP36
SCHEMBL31046884 0.88 KDM1A (0.50) KDM1AACLYUSP2USP8USP36
SCHEMBL23141234 0.87 KDM1A (0.47) KDM1AACLYUSP2USP8USP36
SCHEMBL23877474 0.87 KDM1A (0.49) KDM1AACLYUSP2USP8USP36
SCHEMBL23877599 0.87 KDM1A (0.49) KDM1AACLYUSP2USP8USP36
SCHEMBL23877433 0.87 KDM1A (0.49) KDM1AACLYUSP2USP8USP36

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2026-04-21 — — US disclosed
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO, INC. 2024-12-12 — — US disclosed
US-12049439-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2024-07-30 — — US disclosed
EP-3796975-B1 SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO INC (US) 2023-08-30 — — EP disclosed
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES GILEAD SCIENCES, INC. 2022-02-24 — — US disclosed
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES GILEAD SCIENCES, INC. 2022-02-24 — — US disclosed
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives THE LIVER COMPANY INC. (US) 2021-10-05 — — US disclosed
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives THE LIVER COMPANY INC. (US) 2021-10-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220055985-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B KDM1A 2735/4885ACLY 2228/4885USP2 3178/4885
US-12049439-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B KDM1A 2735/4885ACLY 2228/4885USP2 3178/4885
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives NR3C2, NR5A1, SRD5A2 KDM1A 4072/4885ACLY 1624/4885USP2 3926/4885
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B KDM1A 2735/4885ACLY 2228/4885USP2 3178/4885
US-11136290-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives STS, SULT2A1, SCN2B KDM1A 2735/4885ACLY 2228/4885USP2 3178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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