SCHEMBL31047374

SCHEMBL31047374

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CCC(N)=O)C(=O)O)C(C)C

nearest known ligand 0.66

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.66
▸ VIPR1 P32241 4/20 0.62
▸ BACE1 P56817 2/20 0.62
▸ BACE2 Q9Y5Z0 2/20 0.62
▸ VIPR2 P41587 5/20 0.59
▸ KISS1R Q969F8 9/20 0.59
▸ GLP1R P43220 2/20 0.58
▸ GCGR P47871 1/20 0.58
▸ GIPR P48546 1/20 0.58
▸ ECE1 P42892 1/20 0.58
▸ MUS81 Q96NY9 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30262077 0.95 TFPI (0.67) TFPIVIPR1BACE1BACE2VIPR2
SCHEMBL29893268 0.93 TFPI (0.60) TFPIVIPR1BACE1BACE2VIPR2
SCHEMBL31672198 0.92 BACE1 (0.62) TFPIVIPR1BACE1BACE2VIPR2
SCHEMBL29453341 0.92 VIPR1 (0.72) TFPIVIPR1VIPR2KISS1RGLP1R
SCHEMBL30513687 0.92 KISS1R (0.67) TFPIKISS1R
SCHEMBL29489541 0.92 VIPR1 (0.63) TFPIVIPR1BACE1BACE2VIPR2
SCHEMBL30576938 0.92 TFPI (0.68) TFPIVIPR1VIPR2GLP1RGCGR
SCHEMBL29558454 0.91 TFPI (0.69) TFPIVIPR1BACE1BACE2VIPR2
SCHEMBL30699435 0.91 TFPI (0.60) TFPIVIPR1KISS1RGLP1RGCGR
SCHEMBL30607413 0.91 TFPI (0.66) TFPIVIPR1BACE1BACE2KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240277816-A1 POLYPEPTIDE CONJUGATE AND APPLICATION THEREOF IN PREPARATION OF DRUG FOR TREATING DISEASES RELATED TO GLUCOSE METABOLISM PEGBIO CO., LTD. (CN) 2024-08-22 — — US claimed
US-20240277816-A1 POLYPEPTIDE CONJUGATE AND APPLICATION THEREOF IN PREPARATION OF DRUG FOR TREATING DISEASES RELATED TO GLUCOSE METABOLISM PEGBIO CO., LTD. (CN) 2024-08-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240277816-A1 POLYPEPTIDE CONJUGATE AND APPLICATION THEREOF IN PREPARATION OF DRUG FOR TREATING DISEASES RELATED TO GLUCOSE METABOLISM IAPP, GIPR, GCG TFPI 3899/4885VIPR1 256/4885BACE1 3396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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