Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.53 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11633454 | 0.92 | CA9 (0.50) | BCHEKCNN4KCNA3MAPTLMNA | |
| SCHEMBL31047662 | 0.86 | P2RX4 (0.55) | BCHECYP1A2CYP2C9LMNANPC1 | |
| SCHEMBL9686147 | 0.86 | P2RX4 (0.55) | BCHECYP1A2CYP2C9LMNANPC1 | |
| SCHEMBL31047666 | 0.85 | KDM4E (0.46) | BCHEMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18485382 | 0.84 | CA9 (0.54) | BCHEMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31047667 | 0.84 | CA9 (0.54) | BCHEMAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31047665 | 0.83 | GSK3B (0.58) | BCHEMAPTHTTCES2CES1 | |
| SCHEMBL31047664 | 0.83 | POLB (0.47) | CES2CES1NPC1RAB9AALDH1A1 | |
| SCHEMBL11576538 | 0.83 | P2RX4 (0.54) | MAPTCYP1A2CYP2C9CYP2C19LMNA | |
| SCHEMBL31047659 | 0.83 | ALDH1A1 (0.43) | BCHEKCNN4KCNA3MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496146-A | Preparation method of isoindoline diketone compound | 五邑大学 | 2024-08-16 | — | — | CN | claimed |
| CN-118496146-A | Preparation method of isoindoline diketone compound | 五邑大学 | 2024-08-16 | — | — | CN | disclosed |