Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11751298 | 0.83 | ALOX15 (0.43) | NQO2ERN1ALOX15PIM1MAPT | |
| SCHEMBL4963546 | 0.79 | NQO2 (0.60) | NQO2ALOX15ESR1ESR2CYP1A2 | |
| SCHEMBL31037129 | 0.79 | NQO2 (0.60) | NQO2ALOX15ESR1ESR2CYP1A2 | |
| SCHEMBL1699670 | 0.79 | ERN1 (0.43) | ERN1ALOX15PIM1MAPTMEN1 | |
| SCHEMBL11059407 | 0.79 | MEN1 (0.42) | NQO2ERN1ALOX15PIM1MAPT | |
| SCHEMBL1461934 | 0.76 | ERN1 (0.52) | ERN1ALOX15MAPTMEN1KMT2A | |
| SCHEMBL12693896 | 0.75 | TRPM4 (0.63) | NQO2ERN1ALOX15PIM1MEN1 | |
| SCHEMBL31504060 | 0.75 | TRPM4 (0.63) | NQO2ERN1ALOX15PIM1MEN1 | |
| SCHEMBL30018173 | 0.75 | TMPRSS4 (0.43) | ERN1ALOX15PIM1MAPTMEN1 | |
| SCHEMBL27619808 | 0.75 | PRMT1 (0.59) | ERN1ALOX15PIM1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178304-A1 | KRAS MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-08-29 | — | — | WO | disclosed |