Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19010013 | 0.90 | NPC1 (0.74) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL19010019 | 0.88 | NPC1 (0.72) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7176793 | 0.84 | NPC1 (0.67) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL15883113 | 0.84 | NPC1 (0.67) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL14877791 | 0.84 | NPC1 (0.67) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28700998 | 0.83 | NPC1 (0.65) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28674499 | 0.83 | NPC1 (0.65) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL27865678 | 0.83 | NPC1 (0.65) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28701001 | 0.83 | NPC1 (0.65) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL25746568 | 0.83 | NPC1 (0.65) | NPC1MAPTRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994044-A | O-biphenyl oxazoline compound and synthesis method thereof | 科莱博(江苏)科技股份有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2024159724-A1 | O-BIPHENYL OXAZOLINE COMPOUND AND SYNTHESIS METHOD THEREFOR | 科莱博(江苏)科技股份有限公司 | 2024-08-08 | — | — | WO | disclosed |