Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19010019 | 0.98 | NPC1 (0.72) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL14877791 | 0.90 | NPC1 (0.67) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7176793 | 0.90 | NPC1 (0.67) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL15883113 | 0.90 | NPC1 (0.67) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31048501 | 0.90 | NPC1 (0.67) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28701001 | 0.89 | NPC1 (0.65) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28674499 | 0.89 | NPC1 (0.65) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28700998 | 0.89 | NPC1 (0.65) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL27865678 | 0.89 | NPC1 (0.65) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL25746568 | 0.89 | NPC1 (0.65) | NPC1MAPTRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250320241-A1 | OXYGEN SENSING MATERIALS AND METHODS OF USE | CONWAY DAVID JONATHAN (US) | 2025-10-16 | — | — | US | disclosed |
| US-10647733-B2 | Metal-organic frameworks containing nitrogen-donor ligands for efficient catalytic organic transformations | THE UNIVERSITY OF CHICAGO (US) | 2020-05-12 | — | — | US | disclosed |
| US-20170182486-A1 | METAL-ORGANIC FRAMEWORKS CONTAINING NITROGEN-DONOR LIGANDS FOR EFFICIENT CATALYTIC ORGANIC TRANSFORMATIONS | THE UNIVERSITY OF CHICAGO (US) | 2017-06-29 | — | — | US | disclosed |
| US-20170182486-A1 | METAL-ORGANIC FRAMEWORKS CONTAINING NITROGEN-DONOR LIGANDS FOR EFFICIENT CATALYTIC ORGANIC TRANSFORMATIONS | THE UNIVERSITY OF CHICAGO (US) | 2017-06-29 | — | — | US | disclosed |
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-06-22 | — | — | US | disclosed |
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170173572-A1 | CHIRAL LIGAND-BASED METAL-ORGANIC FRAMEWORKS FOR BROAD-SCOPE ASYMMETRIC CATALYSIS | POF1B, FGFR1, COASY | NPC1 4491/4885MAPT 4198/4885RAB9A 3511/4885 |
| US-10647733-B2 | Metal-organic frameworks containing nitrogen-donor ligands for efficient catalytic organic transformations | NCLN, MDH1, NNMT | NPC1 2864/4885MAPT 2571/4885RAB9A 4263/4885 |
| US-20170182486-A1 | METAL-ORGANIC FRAMEWORKS CONTAINING NITROGEN-DONOR LIGANDS FOR EFFICIENT CATALYTIC ORGANIC TRANSFORMATIONS | NCLN, MDH1, NNMT | NPC1 2864/4885MAPT 2571/4885RAB9A 4263/4885 |
| US-20250320241-A1 | OXYGEN SENSING MATERIALS AND METHODS OF USE | MAVS, LPO, DLD | NPC1 3736/4885MAPT 4795/4885RAB9A 2518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.