Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | UBE2I | P63279 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288117 | 1.00 | HPGD (0.57) | HPGDEGLN1LMNASMN1; SMN2MAPT | |
| SCHEMBL31451668 | 0.78 | HDAC1 (0.62) | HPGDSMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL3359400 | 0.78 | HPGD (0.63) | HPGDSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL15327108 | 0.77 | EGLN1 (0.66) | HPGDEGLN1LMNASMN1; SMN2MAPT | |
| SCHEMBL450428 | 0.76 | HPGD (0.61) | HPGDSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL30437811 | 0.76 | MAPT (0.52) | EGLN1LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL31048490 | 0.74 | MEN1 (0.40) | HPGDSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL25286439 | 0.74 | MEN1 (0.40) | HPGDSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL27999859 | 0.74 | HPGD (0.72) | HPGDEGLN1LMNASMN1; SMN2MAPT | |
| SCHEMBL7655824 | 0.74 | HPGD (0.61) | HPGDSMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954810-A | Regulator of fused ring derivative, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-118302427-A | Fused ring derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-07-05 | — | — | CN | disclosed |