SCHEMBL31048871

SCHEMBL31048871

C[C@H](C(=O)O)N(C(=O)OC(C)(C)C)c1cccnc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TBXAS1 P24557 2/20 0.39
NAMPT P43490 1/20 0.38
ALDH1A1 P00352 3/20 0.37
APP P05067 1/20 0.37
GAA P10253 1/20 0.37
HCAR3 P49019 1/20 0.37
HCAR2 Q8TDS4 1/20 0.37
MAPT P10636 1/20 0.37
CYP3A4 P08684 5/20 0.37
LMNA P02545 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7156656 1.00 HTT (0.39) HTTRAB9AMEN1KMT2ATBXAS1
SCHEMBL1116491 1.00 HTT (0.39) HTTRAB9AMEN1KMT2ATBXAS1
SCHEMBL642839 0.84 SMN1; SMN2 (0.41) RAB9AMEN1KMT2AALDH1A1CYP3A4
SCHEMBL9382586 0.84 SMN1; SMN2 (0.41) RAB9AMEN1KMT2AALDH1A1CYP3A4
SCHEMBL3362092 0.83 F2 (0.38) KMT2AALDH1A1LMNAKDM4E
SCHEMBL28646966 0.83 USP30 (0.37) HCAR2
SCHEMBL3362088 0.83 F2 (0.38) KMT2AALDH1A1LMNAKDM4E
SCHEMBL28646970 0.83 USP30 (0.37) HCAR2
SCHEMBL28817540 0.81 HTT (0.38) HTTRAB9AMEN1KMT2ATBXAS1
SCHEMBL7769274 0.80 HTT (0.44) HTTTBXAS1ALDH1A1APPGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118359535-A Synthesis method of N-tert-butoxycarbonyl-3-pyridyl-D/L-alanine 武汉理工大学 2024-07-19 CN disclosed