Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7156656 | 0.81 | HTT (0.39) | HTTRAB9ATBXAS1CYP3A4MEN1 | |
| SCHEMBL1116491 | 0.81 | HTT (0.39) | HTTRAB9ATBXAS1CYP3A4MEN1 | |
| SCHEMBL31048871 | 0.81 | HTT (0.39) | HTTRAB9ATBXAS1CYP3A4MEN1 | |
| SCHEMBL28471297 | 0.74 | MMP2 (0.41) | RAB9A | |
| SCHEMBL2230081 | 0.73 | TBXAS1 (0.42) | TBXAS1 | |
| SCHEMBL9571667 | 0.73 | RAB9A (0.45) | HTTRAB9ACYP3A4KMT2A | |
| SCHEMBL7645503 | 0.72 | TBXAS1 (0.40) | HTTTBXAS1HDAC6 | |
| SCHEMBL27751076 | 0.72 | SMN1; SMN2 (0.39) | RAB9ACYP3A4MEN1KMT2A | |
| SCHEMBL1529415 | 0.72 | PTGIR (0.49) | HTTRAB9APTGIR | |
| SCHEMBL25178693 | 0.72 | CYP3A4 (0.44) | TBXAS1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102712595-B | Novel compositions for reducing A beta 42 production and their use in treating alzheimer's disease (AD) | KAREUS THERAPEUTTICS SA | 2015-04-22 | — | — | CN | disclosed |