Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 5/20 | 0.32 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049255 | 0.93 | JAK1 (0.35) | KRAS | |
| SCHEMBL31504162 | 0.87 | KRAS (0.38) | KRASMAPK3MAPK1 | |
| SCHEMBL31049099 | 0.84 | JAK1 (0.34) | KRASMAPK3MAPK1 | |
| SCHEMBL31048893 | 0.83 | JAK1 (0.35) | KRASMAPK3MAPK1 | |
| SCHEMBL31048942 | 0.83 | JAK1 (0.35) | KRASMAPK3MAPK1 | |
| SCHEMBL25308840 | 0.83 | KRAS (0.41) | KRASMAPK3MAPK1 | |
| SCHEMBL31049047 | 0.82 | JAK1 (0.34) | KRASMAPK3MAPK1 | |
| SCHEMBL30863988 | 0.82 | KRAS (0.37) | KRASMAPK3MAPK1 | |
| SCHEMBL30864130 | 0.82 | KRAS (0.44) | KRASMAPK3MAPK1 | |
| SCHEMBL31049060 | 0.82 | JAK1 (0.33) | KRASMAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024167922-A2 | HETEROCYCLIC COMPOUNDS AS NRAS INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2024-08-15 | — | — | WO | disclosed |