Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 20/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31493993 | 0.92 | KRAS (0.36) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25308840 | 0.91 | KRAS (0.41) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL27158511 | 0.90 | KRAS (0.42) | KRAS | |
| SCHEMBL30864110 | 0.89 | KRAS (0.44) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL31504155 | 0.89 | KRAS (0.45) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30864130 | 0.89 | KRAS (0.44) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30864111 | 0.89 | KRAS (0.37) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL30863988 | 0.89 | KRAS (0.37) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25300882 | 0.88 | KRAS (0.55) | KRASMAPK3MAPK1RAF1 | |
| SCHEMBL25297310 | 0.88 | KRAS (0.47) | KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025083472-A2 | PROTAC COMPOUNDS BINDING KEAP1 UBIQUITIN LIGASE FOR TARGETED PROTEIN DEGRADATION | SEED THERAPEUTICS US, INC. (US) | 2025-04-24 | — | — | WO | disclosed |