Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16036772 | 0.80 | FGFR1 (0.55) | HTTPOLBFGFR1MKNK1MKNK2 | |
| SCHEMBL7472749 | 0.74 | HTT (0.55) | HTTPOLBFGFR1ROCK1MKNK1 | |
| SCHEMBL2465676 | 0.72 | MKNK2 (0.67) | HTTPOLBFGFR1ROCK1MKNK1 | |
| SCHEMBL30402227 | 0.71 | HTT (0.88) | HTTPOLBFGFR1ALDH1A1 | |
| SCHEMBL3419279 | 0.71 | HTT (0.88) | HTTPOLBFGFR1ALDH1A1 | |
| SCHEMBL3417306 | 0.71 | HTT (0.73) | HTTPOLBFGFR1ROCK1MKNK1 | |
| SCHEMBL24988386 | 0.71 | HTT (0.60) | HTTPOLBFGFR1ROCK1MKNK1 | |
| Hydrochloric Acid SCHEMBL2491050 | 0.71 | MKNK2 (0.65) | HTTPOLBFGFR1ROCK1MKNK1 | |
| SCHEMBL1803928 | 0.70 | HTT (0.55) | HTTPOLBFGFR1ROCK1MKNK1 | |
| SCHEMBL9025863 | 0.70 | PIK3CB (0.68) | HTTPOLBFGFR1ROCK1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359627-A | MTA synergistic PRMT5 inhibitor compounds having a tetracyclic fused ring structure | 烨辉医药科技(上海)有限公司 | 2024-07-19 | — | — | CN | disclosed |