Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049363 | 0.87 | HDAC6 (0.43) | EGFRHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29267244 | 0.76 | HDAC6 (0.42) | HPGDNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL31049440 | 0.75 | SCN9A (0.32) | SCN9AKMT2AMEN1TERT | |
| SCHEMBL31024612 | 0.72 | NPC1 (0.44) | HPGDNPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL31024611 | 0.72 | NPC1 (0.44) | HPGDNPC1RAB9ASMN1; SMN2CYP1A2 | |
| Lithium Ion SCHEMBL31049392 | 0.71 | PTGDR2 (0.35) | RAB9ASMN1; SMN2CYP2C9MAPK1POLB | |
| SCHEMBL31049474 | 0.70 | CXCR2 (0.38) | NPC1RAB9ASMN1; SMN2MAPK1POLB | |
| SCHEMBL31537863 | 0.69 | MAPT (0.42) | EGFRHPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31049368 | 0.69 | CXCR2 (0.35) | HPGDNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL31049309 | 0.69 | CA12 (0.33) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173453-A1 | HETEROARYL-SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2024-08-22 | — | — | WO | disclosed |