Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049368 | 0.88 | CXCR2 (0.35) | CXCR2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL31258801 | 0.87 | ALDH1A1 (0.38) | CXCR2MEN1KMT2AHTTHDAC3 | |
| SCHEMBL31049390 | 0.86 | CXCR2 (0.34) | CXCR2MAPTSMN1; SMN2MEN1KMT2A | |
| Lithium Ion SCHEMBL31049392 | 0.86 | PTGDR2 (0.35) | CXCR2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL31258706 | 0.85 | KMT2A (0.35) | CXCR2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL31024612 | 0.82 | NPC1 (0.44) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL31024611 | 0.82 | NPC1 (0.44) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL30713264 | 0.76 | CA12 (0.40) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL31258705 | 0.75 | MEN1 (0.34) | CXCR2MEN1KMT2AMAPK1HDAC3 | |
| SCHEMBL30967347 | 0.74 | ALDH1A1 (0.39) | CXCR2MAPTSMN1; SMN2MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173453-A1 | HETEROARYL-SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS | IDEAYA BIOSCIENCES, INC. (US) | 2024-08-22 | — | — | WO | disclosed |