Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.40 |
| ▸ | USP20 | Q9Y2K6 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.34 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049545 | 0.81 | AURKA (0.46) | IDO1HPGDSCDK1CDK2SCN4A | |
| SCHEMBL31049324 | 0.76 | DYRK1A (0.42) | NOTUMHPGDSCDK1CDK2SCN4A | |
| SCHEMBL1606453 | 0.74 | TDO2 (0.52) | CYP19A1HPGDHTR2AHTR2CKCNH2 | |
| SCHEMBL1814795 | 0.70 | NOTUM (0.59) | IDO1NOTUMHPGDSSCN4A | |
| SCHEMBL31049308 | 0.70 | USP20 (0.45) | USP20CCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL23885700 | 0.70 | USP20 (0.66) | USP20CCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL1810095 | 0.65 | NOTUM (0.51) | IDO1NOTUMHPGDSSCN4A | |
| Hydrochloric Acid SCHEMBL13733073 | 0.64 | NOTUM (0.50) | IDO1NOTUMHPGDSSCN4A | |
| SCHEMBL2126317 | 0.63 | KDM5A (0.57) | ALDH1A1 | |
| SCHEMBL16252839 | 0.62 | MAP2K4 (0.51) | NTRK1ITKHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359627-A | MTA synergistic PRMT5 inhibitor compounds having a tetracyclic fused ring structure | 烨辉医药科技(上海)有限公司 | 2024-07-19 | — | — | CN | disclosed |