SCHEMBL31049446

SCHEMBL31049446

CNC(=O)[C@H]1CN(c2cc(S(=O)(=O)NC3(C)CC3)cn3c(-c4nnc(C(F)F)s4)cnc23)C[C@@H](C)O1

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PARG Q86W56 8/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31049498 0.93 PARG (0.39) PARG
SCHEMBL31049490 0.93 PARG (0.39) PARG
SCHEMBL31049635 0.89 PARG (0.38) PARG
SCHEMBL31049413 0.89 PARG (0.38) PARG
SCHEMBL31049355 0.88 PARG (0.39) PARG
SCHEMBL31049471 0.88 PARG (0.39) PARG
SCHEMBL31049320 0.88 PARG (0.39) PARG
SCHEMBL31049493 0.88 PARG (0.38) PARG
SCHEMBL31288223 0.85 PARG (0.40) PARG
SCHEMBL31288348 0.85 PARG (0.40) PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024173453-A1 HETEROARYL-SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS IDEAYA BIOSCIENCES, INC. (US) 2024-08-22 WO disclosed