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Sugi Predict / Compounds / SCHEMBL31049490

SCHEMBL31049490

SCHEMBL31049490

C[C@@H]1CN(c2cc(S(=O)(=O)NC3(C)CC3)cn3c(-c4nnc(C(F)F)s4)cnc23)C[C@H](C(N)=O)O1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PARG Q86W56 13/20 0.39
▸ EIF2AK4 Q9P2K8 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31049498 1.00 PARG (0.39) PARGEIF2AK4
SCHEMBL31049446 0.93 PARG (0.38) PARG
SCHEMBL31049493 0.89 PARG (0.38) PARGEIF2AK4
SCHEMBL31049520 0.89 PARG (0.39) PARG
SCHEMBL31049405 0.89 PARG (0.39) PARG
SCHEMBL31049466 0.88 PARG (0.40) PARG
SCHEMBL31049489 0.88 PARG (0.40) PARG
SCHEMBL31049429 0.88 PARG (0.40) PARG
SCHEMBL31288223 0.86 PARG (0.40) PARG
SCHEMBL31288348 0.86 PARG (0.40) PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024173453-A1 HETEROARYL-SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS IDEAYA BIOSCIENCES, INC. (US) 2024-08-22 — — WO disclosed